Sono state annunciate circa una sessantina di canzoni che saranno incluse in "Guitar Hero 5", videogioco in arrivo a settembre:

2 Minutes to Midnight - Iron Maiden
21st Century Schizoid Man - King Crimson
A-Punk - Vampire Weekend
All Along the Watchtower - Bob Dylan
All The Pretty Faces - The Killers
American Girl - Tom Petty and the Heartbreakers
Back Around - Wolfmother
Blue Day - Darker My Love
Blue Orchid - The White Stripes
Brianstorm - Arctic Monkeys
Bring The Noise - Public Enemy feat Zakk Wylde
Cigarettes, Wedding Bands - Band of Horses
Deadbolt - Thrice
Demon(s) - Darkest Hour
Disconnected - Face to Face
Done With Everything, Die for Nothing - Children of Bodom
Du Hast - Rammstein
Fame - David Bowie
Gamma Ray - Beck
Ghost Town - Shiny Toy Guns
Gratitude - Beasty Boys
Hurt So Good - John Mellencamp
In My Place - Coldplay
Incinerate - Sonic Youth
Inside Out - Eve 6
Jailbreak - Thin Lizzy
Jimmy - M.I.A.
Judith - A Perfect Circle
L.A. - Elliott Smith
Lithium (live) - Nirvana
Lonely Is The Night - Billy Squier
Lust For Life (live) - Iggy Pop
Maiden, Mother & Crone - The Sword
Make It Wit Chu - Queens Of The Stone Age
Mirror People - Love and Rockets
Muse - Plug in Baby
Nearly Lost You - Screaming Trees
Never Miss A Beat - Kaiser Chiefs
No One to Depend On (live) - Santana
One Big Holiday - My Morning Jacket
Only Happy When It Rains - Garbage
Ring of Fire - Johnny Cash
The Rock Show - Blink 182
Runnin' Down a Dream - Tom Petty
Saturday Night's Alright (For Fighting) - Elton John
Scatterbrian (live) - Jeff Beck
Send A Little Love Token - The Duke Spirit
Sex on Fire - Kings of Leon
Shout It Out Loud - Kiss
Six Days A Week - The Bronx
Sneak Out - Rose Hill Drive
So Lonely - The Police
Song 2 - Blur
Superstition - Stevie Wonder
Sympathy for the Devil - Rolling Stones
Under Pressure - Queen e David Bowie
What I Got - Sublime
Wolf Like Me - Tv on the Radio
Woman From Tokyo ('99 Remix) - Deep Purple
You And Me - Attack! Attack!
You Give Love A Bad Name - Bon Jovi

Come vi abbiamo riportato in precedenza, è già noto inoltre che saranno presenti anche i seguenti artisti, dei quali devono ancora essere annunciate le canzoni:

3 Doors Down
AFI
Billy Idol
Brand New
Bush
The Derek Trucks Band
Dire Straits
Duran Duran
Eagles of Death Metal
Gorillaz
Gov't Mule
Grand Funk Railroad
Jimmy Eat World
Megadeth
Mötley Crüe
No Doubt
Peter Frampton
The Raconteurs
Rush
Scars on Broadway
The Smashing Pumpkins
Spacehog
Sunny Day Real Estate
T.Rex
Weezer
Wild Cherry